supranuclear palsy care at Mayo Clinic. 18, both developed parkinsonism in the eighth decade of life and subsequently exhibited typical features of PSP over the next 5 years. New symptoms can also develop at this stage, such as: Advanced stages, as PSP progresses to an advanced stage, people with the condition normally begin to experience increasing difficulties controlling the muscles of their mouth, throat and tongue. Researchers have found that the deteriorating brain cells of people with progressive supranuclear palsy have abnormal amounts of a protein called tau. Although most cases of PSP appear to be sporadic, rare genetically determined forms may exist. In one case-control questionnaire, a trend toward relatives with parkinsonism was reported. Depression and anxiety, a surprised or frightened facial expression, resulting from pentateuch Women rigid facial muscles. Kaat et al reported that of 57 (33) of 172 patients with PSP had at least 1 first-degree relative who had dementia or parkinsonism, compared with 25 of control subjects. Pupils of the eyes different size. Request an Appointment at Mayo Clinic.
Progressive Supranuclear Palsy
Males and females are. What is progressive supranuclear palsy?
Because its early symptoms may look similar to those of Parkinson's disease or Alzheimer's disease, it is often initially misdiagnosed as one of these two diseases. Speech may become increasingly slow and slurred, making it harder to understand. . Rarely, progressive supranuclear palsy occurs within a family. The speech therapist can also offer the PSP patient alternative communication devices, such as pointing boards or computer-based systems. Most people with the condition won't experience all of these. The cause of PSP remains unknown. The condition tends to develop gradually, which means it can be mistaken for another, more common, condition at first. Tests may be done to rule out other diseases. Stiffness and rigid movement in the neck, trunk, arms, legs. 20, in the cohort studied by Kaat et al, 12 of 172 patients with PSP (7) fulfilled the criteria for an autosomal dominant mode of transmission.